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目的探讨多层螺旋CT(MSCT)在测定左心室整体功能中的应用价值。方法对29例临床确诊或怀疑冠心病的患者行64层螺旋CT回顾性心电门控增强扫描,用舒张末期和收缩末期重建像计算左室舒张末容积(LVEDV)、左室收缩末容积(LVESV)、左室每搏量(LVSV)和左室射血分数(LVEF),并与同期X线左心室造影(LVG)结果进行比较。结果64层螺旋CT与LVG在测定左室容积和功能方面具有高度相关性(r=0.887～0.956,P<0.001)。BlandAltman法结果显示,64层螺旋CT与LVG测定LVEDV、LVESV、LVSV和LVEF差值的平均数分别是-2.3ml、4.1ml、-6.4ml和-3.5%,两种检查方法一致性范围分别是-27.2～22.4ml、-10.2～18.4ml、-26.4～13.6ml和-9.8%～3.0%。结论MSCT与LVG在评价左心室整体功能方面的一致性可被临床接受。
Objective To investigate the value of multi-slice spiral CT (MSCT) in the determination of left ventricular global function. Methods Twenty-nine patients with clinically diagnosed or suspected coronary heart disease underwent retrospective electrocardiographic gated augmentation scan with 64-slice spiral CT. Left ventricular end-diastolic volume (LVEDV) and left ventricular end-systolic volume (LVEDV) were measured by end-diastolic and end- LVESV, left ventricular stroke volume (LVSV) and left ventricular ejection fraction (LVEF), and compared with the results of the same period of the left ventricular angiography (LVG). Results 64-slice spiral CT was highly correlated with LVG in determining left ventricular volume and function (r = 0.887-0.9565, P <0.001). BlandAltman method showed that the mean values of LVEDV, LVESV, LVSV and LVEF measured by 64-slice spiral CT and LVG were -2.3ml, 4.1ml, -6.4ml and -3.5%, respectively. The consistency of the two methods were -27.2 to 22.4 ml, -10.2 to 18.4 ml, -26.4 to 13.6 ml and -9.8% to 3.0%. Conclusions The agreement between MSCT and LVG in assessing the overall LV function may be clinically accepted.