为了阐明控制细粒棘球绦虫发育和生长的机制,作者对该寄生虫的同源框基因进行了研究。 同源框基因是DNA的基序,编码60个氨基酸长短的一段序列(同源序列)。它们在转录因子的大家族中被人们发现,通过同源序列本身结合到靶基因的5′端调节序列,以调节基因表达。 In order to elucidate the mechanism that controls the development and growth of Echinococcus granulosus, the authors studied the homologue gene of this parasite. Homologous box genes are DNA motifs that encode a 60-amino acid sequence (homologous sequence). They are found in large families of transcription factors that regulate gene expression by binding to the 5 ’regulatory sequences of the target genes themselves by homologous sequences.