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目的探讨妇女增补叶酸预防神经管畸形。方法对1994年元月至1996年12月准备怀孕妇女及经产妇再次怀孕未服用小剂量叶酸片18268人跟踪随访,以及对1997年元月至2002年12月准备怀孕妇女及经产妇再次怀孕前服用小剂量叶酸片37461人孕情跟踪服务,结果证实,三年来未服用小剂量叶酸片的妇女生育神经管畸形儿104人,神经管畸形率5.7‰,而从1997~2002年6年间全部服用小剂量叶酸片的妇女生育神经管畸形64人,神经管畸形率1.7‰,明显降低,可见,妇女增补小剂量叶酸能有效地预防神经管畸形的发生。
Objective To investigate the effect of folic acid supplementation on preventing neural tube defects in women. Methods From January 1994 to December 1996, 18268 pregnant women and pregnant women who did not take small doses of folic acid were enrolled in this study. Follow-up was performed for 18268 pregnant women and pregnant women before pregnancy again from January 1997 to December 2002 Take small doses of folic acid tablets 37461 pregnancy tracking service, the results confirmed that three years did not take small doses of folic acid tablets in children with reproductive neural tube defects in 104 children, the rate of neural tube defects 5.7 ‰, and from 1997 to 2002 all 6 years of taking Small doses of folic acid tablets women reproductive neural tube defects in 64 people, the rate of neural tube defects 1.7 ‰, significantly lower, we can see that women with small doses of folic acid can effectively prevent the occurrence of neural tube defects.