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甜味剂天冬甜素的合成方法主要有化学合成和酸法合成两大类．本文对化学合成法中五种具有代表性的合成方法进行了实验探讨，并对以不同原料进行缩合反应中间体及最终产物的产率作了研究比较。
Aspartame sweetener synthesis methods are mainly chemical synthesis and acid synthesis of two categories. In this paper, five representative synthetic methods in chemical synthesis were discussed experimentally, and the yields of intermediates and final products with different raw materials for condensation reaction were compared.