论文部分内容阅读
[目的]评价阴道镜下活检诊断宫颈上皮内瘤变(CIN)的准确性。[方法]回顾性分析阴道镜下活检诊断为CIN,并于短期内行LEEP160例患者的临床病理资料;对比评价阴道镜下活检和最终病理结果,并分析阴道镜下宫颈活检漏诊浸润性宫颈癌的相关因素。[结果]160例患者阴道镜下宫颈活检病理诊断与最终诊断符合率为69.4%(111/160),不符合率为30.6%(49/160)。160例患者最终诊断为宫颈浸润癌18例,漏诊率为11.3%。细胞学检查结果为高度鳞状上皮内病变(HSIL)及以上病变者、病灶累及腺体和多个病灶级别并存与阴道镜下宫颈活检浸润癌的漏诊发生显著相关。[结论]阴道镜下活检对确诊CIN尚不够准确,存在宫颈浸润癌漏诊的可能。
[Objective] To evaluate the accuracy of colposcopic biopsy in diagnosing cervical intraepithelial neoplasia (CIN). [Methods] A retrospective analysis of colposcopy biopsy diagnosed as CIN, and in the short term clinical data of LEEP 160 patients; collateral biopsy and final pathological evaluation of colorectal biopsy results and analysis of colposcopic biopsy missed invasive cervical cancer relevant factor. [Results] The coincidence rate of colposcopic biopsy and final diagnosis of colposcopy was 69.4% (111/160) and 30.6% (49/160) in 160 patients. The final diagnosis of 160 cases of cervical invasive carcinoma in 18 cases, the missed diagnosis rate was 11.3%. The results of cytology were highly associated with squamous intraepithelial lesion (HSIL) and above. The coexistence of lesion involving the gland and multiple lesion was significantly associated with missed diagnosis of invasive cervical cancer by colposcopy. [Conclusion] Colposcopy biopsy is not accurate enough to diagnose CIN, so there is a possibility of misdiagnosis of cervical invasive carcinoma.