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目的 老年性 (6 0～ 82岁 )脑梗死住院患者血浆中凝血酶敏感蛋白 (TS)水平与脑梗死形成、病情及病程关系。方法 采用流式细胞术检测 6 0例老年性脑梗死患者血浆TS水平。结果 老年性脑梗死组血浆中血小板膜TS水平显著高于对照组 (P <0 0 1) ;重病人组又略高于轻病人组 (P <0 0 5 ) ;病后 6h组高于患病大于 96h组 (P <0 0 5 )。结论 血小板膜TS改变参与了脑血栓形成过程 ;血浆TS水平的异常增高可随病情的加重而升高 ,随病程的延长而下降。提示血浆中TS增高可能为脑梗死早期诊断和治疗的指标之一。
Objective To investigate the relationship between plasma thromboplastin (TS) levels and cerebral infarction in elderly patients (60 ~ 82 years old) with cerebral infarction. Methods Flow cytometry was used to detect plasma TS levels in 60 elderly patients with cerebral infarction. Results Compared with the control group, the level of platelet membrane TS in plasma of senile cerebral infarction group was significantly higher than that of the control group (P <0.01), slightly higher in the severe patient group than in the mild patient group (P <0.05) The disease was greater than 96h group (P <0 05). Conclusions The TS of platelet membrane is involved in the process of cerebral thrombosis. The abnormal increase of plasma TS level may increase with the severity of the disease and decrease with the prolongation of the course of disease. Tip TS in plasma may be an early diagnosis and treatment of cerebral infarction one of the indicators.