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目的 :探讨重症肌无力患儿的免疫状态及免疫调节治疗的效果。方法 :对 15例重症肌无力儿童接受免疫调节治疗前后血清可溶性白细胞介素 受体 (s IL - 2 R)进行了检测 ,结果 :本组患儿 s IL - 2 R治疗前明显增高 ,获得缓解后 s IL - 2 R近于正常水平。结论 :此病患儿免疫调节功能紊乱 ,s IL- 2 R可成为免疫调节治疗的有效观察指标 ,免疫调节治疗达到目的
Objective: To investigate the immune status of children with myasthenia gravis and the effect of immunomodulatory therapy. Methods: Serum soluble interleukin - 2 receptor (IL - 2R) were measured in 15 children with myasthenia gravis before and after immunosuppressive therapy. Results: The levels of s IL - 2 R in children with myasthenia gravis were significantly higher than those before treatment After the s IL - 2 R nearly normal levels. Conclusion: The immunosuppressive disorder in children with this disease, s IL-2 R immunosuppressive therapy can be an effective indicator of immunomodulation therapy to achieve the purpose