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目的 :观察龙马自来胶囊对实验性脊髓损伤的影响。方法 :用龙马自来胶囊治疗脊髓损伤 ,观察脊髓神经功能及组织学变化。结果 :神经功能评分及脊髓传导功能未见明显改变。组织学观察 ,中药组较空白组水肿液化减少 ,但脊髓出血增多 ,并在脊髓灰质中间观察到新生的毛细血管 ;激素组脊髓水肿轻 ,但明显萎缩 ;激素加中药组脊髓水肿不明显 ,无脊髓萎缩现象。结论 :龙马自来胶囊虽然未能显示有效的改善脊髓功能 ,但可减轻激素在脊髓损伤治疗中的副作用 ,改善脊髓局部的血流情况。
Objective: To observe the effect of Longma Zilai Capsule on experimental spinal cord injury. Methods: Spinal cord injury was treated with Longma Zilai Capsule, and neurological function and histological changes of spinal cord were observed. Results: There was no significant change in neurological function score and spinal cord conduction function. Histological observation showed that the Chinese medicine group had less edema and liquefaction than the blank group, but there was an increase in spinal cord hemorrhage and new capillaries were observed in the gray matter of the spinal cord; in the hormone group, the spinal edema was mild, but the atrophy was obvious; the spinal cord edema in the hormone plus Chinese medicine group was not obvious. Spinal cord atrophy. Conclusion: Although Longma Zi Lai Capsules failed to show effective improvement of spinal cord function, it can reduce the side effects of hormones in the treatment of spinal cord injury and improve the blood flow in the spinal cord.