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超氧化物歧化酶(superoxide dismutase,SOD)是新近发现的一类抗氧化酶,是一种重要的氧自由基清除剂。目前国内外已建立起一套快速而有效的分离SOD及检测的方法,并对其化学、药理、临床及作用机理等进行了一系列研究。 1.SOD的一般特性各种生物体利用分子氧的第一步是通过还原型铺酶Ⅰ,在超氧阴离子合成酶的作用下,先形成分子氧,其本身无甚毒性,但其还原
Superoxide dismutase (SOD) is a newly discovered class of antioxidant enzymes, is an important oxygen free radical scavenger. At present, a set of rapid and effective methods for separating SOD and its detection has been established at home and abroad, and a series of researches on its chemical, pharmacological, clinical and mechanism of action have been carried out. 1. The general characteristics of SOD The first step in the utilization of molecular oxygen by various organisms is the formation of molecular oxygen under the action of superoxide anion synthase by reducing type I enzyme, which itself is not very toxic but its reduction