BACKGROUND:Upper gastrointestinal(GI)bleeding is a common complication of portal hypertension in cirrhotic patients,and hepatocellular carcinoma(HCC)is the most common tumor in cirrhotic livers.Bleeding from tumor erosion into the GI tract is very rare.A patient with HCC and gastric tumor invasion was described and the previously reported cases were reviewed. METHOD:A patient with upper GI bleeding was treated in a tertiary hospital. RESULTS:A cirrhotic patient with a HCC invading the stomach leading to upper GI bleeding was treated by left lateral segmentectomy and sub-total gastrectomy.The bleeding was controlled and a good surgical outcome was achieved. CONCLUSIONS:HCC with gastric invasion should be differentially diagnosed from upper GI bleeding in cirrhotic patients.Bleeding can be controlled and symptomatic relief marked in selected cases. BACKGROUND: Upper gastrointestinal (GI) bleeding is a common complication of portal hypertension in cirrhotic patients, and hepatocellular carcinoma (HCC) is the most common tumor in cirrhotic livers. Breeding from tumor erosion into the GI tract is very rare. A patient with HCC A patient with upper GI bleeding was treated in a tertiary hospital. RESULTS: A patient with upper GI bleeding was treated in a tertiary hospital. RESULTS: A patient with upper GI bleeding was treated by left lateral segmentectomy and sub-total gastrectomy.The bleeding was controlled and a good surgical outcome was achieved. CONCLUSIONS: HCC with gastric invasion should be differentially diagnosed from upper GI bleeding in cirrhotic patients. Bleeding can be controlled and symptomatic relief marked in selected cases.