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骨髓移植(BMT)后神经并发症的发生率约为30%,作者报告1例all-BMT后出现选择性交感神经自律性神经病,据称这种现象文献中尚未见报道。男性20岁,急性淋巴母细胞白血病患者,FAB分类为L_3型。中枢神经系统无白血病浸润,在接受MACHO方案化疗1.5疗程的3个月内,还接受氨甲喋呤(总量137.5mg)、Ara-C(330mg)和皮质激素鞘内注射.BMT预处理方案包括7.2g环磷酰胺及1400cGy的全身放疗(TBI)。接受HLA匹配的同胞
The incidence of neurological complications after BMT is about 30%. The authors report a case of selective sympathetic autonomic neuropathy after all-BMT. It has been reported that this phenomenon has not been reported in the literature. Male 20 years old, acute lymphoblastic leukemia, FAB classification as L_3 type. Central nervous system infiltration without leukemia, methotrexate (total 137.5mg), Ara-C (330mg), and intrathecal injection of corticosteroids within 3 months of receiving MACHO regimen chemotherapy.BMT preconditioning regimen included 7.2g Cyclophosphamide and 1400 cGy Systemic Radiotherapy (TBI). HLA-matched siblings