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目的:探讨99mTc-甲氧基异丁基异腈(MIBI)门控心肌断层显像在诊断轻症病毒性心肌炎(VMC)中的应用价值。方法:用双探头多功能SPECT仪,对轻症VMC组68例和正常对照组34例进行运动-静息心肌灌注断层显像。结果:VMC组68例中门控心肌断层显像异常者56例,阳性率为82.35%;正常对照组34例心肌显像均未显示异常;2组间比较差异有统计学意义(χ2=62.09,P<0.01)。心肌显像异常者56例中,固定性缺损32例(57.14%),可逆性缺损4例(7.14%),混合性缺损8例(14.29%),反向再分布12例(21.43%);单灶性损害16例(28.57%),多灶性损害40例(71.43%)。结论:运动-静息门控心肌断层显像对轻症急性VMC患者的诊断有较大的临床实用价值。
Objective: To investigate the value of 99mTc-methoxyisobutylisonitrile (MIBI) gated myocardial tomography in the diagnosis of mild viral myocarditis (VMC). Methods: The double-probe multi-function SPECT was used in 68 cases of mild VMC group and 34 cases of normal control group for exercise-resting myocardial perfusion tomography. Results: In the VMC group, 56 patients with gated myocardial imaging were abnormal in 56 cases, the positive rate was 82.35%. There were no abnormalities in myocardial imaging in 34 cases of normal control group. The difference between the two groups was statistically significant (χ2 = 62.09 , P <0.01). Among the 56 cases with abnormal myocardial imaging, 32 cases (57.14%) had fixed defect, 4 cases (7.14%) had reversible defect, 8 cases (14.29%) had mixed defect and 12 cases (21.43%) reversed redistribution. There were 16 cases (28.57%) with single focal lesion and 40 cases (71.43%) with multifocal lesion. Conclusion: Exercise-resting gated myocardial tomography has great clinical value in the diagnosis of mild acute VMC.