流行病学调查发现，停经前女性与同年龄组男性比较，患冠心病的危险性仅为５０％左右；停经后女性发病率迅速上升接近甚至超过男性；高血压病和中风的发生率也明显升高，心血管疾病成为导致死亡的主要原因。临床研究表明，雌激素替代治疗可以减少绝经后女性心血管疾病的发生， Epidemiological survey found that premenopausal women compared with men of the same age group, the risk of suffering from coronary heart disease is only about 50%; the incidence of postmenopausal women rose rapidly approaching or exceeding men; the incidence of hypertension and stroke was also significant Elevated cardiovascular disease is the leading cause of death. Clinical studies have shown that estrogen replacement therapy can reduce the incidence of cardiovascular disease in postmenopausal women,