目的： 验证低剂量利培酮 （≤２ｍ ｇ／ｄ） 治疗首发精神分裂症的疗效。　方法： 对１５ 例符合 Ｉ Ｃ Ｄ１０ 和 Ｃ Ｃ Ｍ Ｄ２ Ｒ 诊断标准的门诊首发病人进行 ８ 周低剂量利培酮治疗， 以阳性症状和阴性症状量表 （ Ｐ Ａ Ｎ Ｓ Ｓ） 等评定疗效和副作用。　结果： 显效率８０％ ， 有效率９３３％ ， 起效时间一周。　结论： 低剂量利培酮治疗首发精神分裂症是可行的和有效的， 且安全性更好。 AIM: To verify the efficacy of low-dose risperidone (≤2 m g / d) in the treatment of first-episode schizophrenia. Methods: 15 outpatients with first-line diagnosis of I C D10 and CMD2R were treated with lowdose risperidone for 8 weeks. Positive and negative symptom scales (P A N S S ) And other assessment of efficacy and side effects. Results: The markedly effective rate of 80%, the effective rate of 933%, the onset time of one week. Conclusions: Low-dose risperidone is feasible and effective in the treatment of first-episode schizophrenia, and its safety is better.