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目的 通过使用中文版计算机神经行为评价系统 (NES C3 )项目的测试 ,探讨锰对职业接触工人神经行为的影响。方法 以 10 0名接锰工人和 2 6名非接锰工人为测试对象 ,然后选取 11个行为测试项目进行测试。将接锰工人按累积暴露指数 (CEI)大小分为低暴露组 (CEI <5 )与高暴露组 (CEI≥ 5 ) ,每名工人由专业人员单独测试。结果 暴露组工人的行为如情绪、符号译码、视简单反应时、目标追踪得分 ,与对照组相比已有明显改变 (P <0 0 5 )。相关分析发现神经行为功能改变与锰累积暴露剂量之间存在剂量效应关系。结论 长期接触锰可引起职业接触工人情感状态、心理运动能力、手眼协调能力的改变。计算机神经行为测试可作为一种检测职业接锰工人神经系统亚临床损害的较理想的方法。
Objective To explore the effect of manganese on the neurological behavior of occupationally exposed workers through the use of a Chinese version of the NES C3 program. Methods One hundred and twenty manganese workers and twenty-six non-connected manganese workers were selected as test subjects and 11 behavioral test items were selected for testing. Manganese workers were divided into low exposure group (CEI <5) and high exposure group (CEI> 5) by cumulative exposure index (CEI) size, with each worker being tested individually by a specialist. Results The behavior of workers in exposed group such as emotion, symbolic decoding, simple target tracking, target tracking score, compared with the control group has been significantly changed (P <0 05). Correlation analysis revealed a dose-response relationship between altered neurobehavioral function and accumulated manganese exposure dose. Conclusion Long-term exposure to manganese can cause changes in emotional status, psychomotor ability, and hand-eye coordination among occupationally exposed workers. Computer neurobehavioral testing can be used as a better way to detect subclinical damage to the occupational nervous system of occupational workers.