十几世纪以来,许多报告将某些肝胆病变与炎性肠道疾病(简称 IBD)的发生联系在一起。1874年Thomas 首先报道溃疡性结肠炎病人患严重肝脏脂肪浸润。1899年 Lister 报道一例溃疡性结肠炎和“继发弥漫性肝炎”的病例。继而,Logan 对117例溃疡性结肠炎进行了复习,其中13例做了尸检,发现11例有肝脏脂肪浸润;1例慢性肝炎;另1例肝硬变。1938乍 Comfort 报道4例溃疡性结肠炎伴有慢性肝 For more than a century, many reports have linked certain hepatobiliary lesions to the development of inflammatory bowel disease (IBD). In 1874 Thomas first reported severe fatty liver infiltration in patients with ulcerative colitis. In 1899 Lister reported a case of ulcerative colitis and “secondary diffuse hepatitis.” In turn, Logan reviewed 117 patients with ulcerative colitis, 13 of whom underwent an autopsy and found that 11 had fatty infiltration of the liver; one had chronic hepatitis and the other had cirrhosis. In 1938, Comfort reported four cases of ulcerative colitis with chronic liver disease