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目的:评价卡前列素氨丁三醇注射液(欣母沛)用于预防前置胎盘剖宫产患者产后出血的临床疗效。方法:选取2013年1月—2014年1月期间产科收治的前置胎盘剖宫产手术患者60例,采用随机数字表法将患者分为治疗组和对照组,各30例;治疗组产妇于胎儿娩出后给予欣母沛宫体注射治疗,对照组产妇于胎儿娩出后给予缩宫素宫体注射与卡前列甲酯栓舌下含化治疗,比较两组患者产后出血情况。结果:治疗组产妇产后2 h和24 h的平均出血量均明显低于对照组(P<0.05),两组产妇用药后不良反应的发生率经比较其差异无统计学意义(P>0.05)。结论:欣母沛用于预防前置胎盘剖宫产患者产后出血疗效较为满意。
Objective: To evaluate the clinical efficacy of carboprost trometamol injection (Xin-Pei-Pei) in the prevention of postpartum hemorrhage in patients with placenta previa. Methods: Sixty patients undergoing cesarean section with placenta accreta in January 2013 to January 2014 were enrolled. Patients were divided into treatment group and control group by random number table method, 30 cases in each group. The treatment group maternal After the fetus was delivered, the mother was given the injection of Yanbian Pei Palace. The control group was treated with oxytocin injection and hypothyroidism with sublingual chemotherapy after the fetus was delivered. The postpartum hemorrhage was compared between the two groups. Results: The average amount of bleeding in the treatment group at 2 h and 24 h postpartum was significantly lower than that in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05) . Conclusion: Xinmaopene is effective in preventing postpartum hemorrhage in patients with placenta previa.