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目的 探讨慢性充血性心力衰竭 (CHF)病人血清甲状腺激素水平及其临床意义。方法 分别测定4 1例CHF病人治疗前后及 30例健康人群的血清甲状腺激素水平 ,并进行对比观察。结果 CHF病人的T3 水平和T3 /rT3 比值明显低于健康对照组 (P >0 0 1) ,而rT3 和T4水平与健康对照组比无明显差别 (P >0 0 5 )。随心功能不全加重 ,病人的T3 ,T3 /rT3 比值逐渐降低 ,rT3 升高 ,心功能Ⅳ级和死亡病人T4水平也明显降低。随病程延长 ,T3 水平降低。
Objective To investigate the serum thyroid hormone level in patients with chronic congestive heart failure (CHF) and its clinical significance. Methods Serum levels of thyroid hormone were measured in 41 patients with CHF before and after treatment and 30 healthy controls respectively. Results The levels of T3 and T3 / rT3 in CHF patients were significantly lower than those in healthy controls (P <0.01), while the levels of rT3 and T4 were not significantly different from those in healthy controls (P> 0.05). Patients with heart dysfunction worsened, patients T3, T3 / rT3 ratio decreased, rT3 increased, cardiac function and death level T4 levels were significantly lower. With the extended duration, T3 decreased.