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采用碱性提取法测量了三磺化铝酞菁(AlS3PC)在正常细胞和肿瘤细胞内的代谢比,得到了AlS3PC在正常细胞和肿瘤细胞内最高潴留浓度的时间,可作为PDT治疗肿瘤的最佳时间,另外通过测试得到的数据,建立了一套有关细胞膜的通透性模型,用以解释肿瘤细胞对AlS3PC的亲和性。
AlS3PC was used to measure the metabolic ratio of AlS3PC in normal cells and tumor cells using alkaline extraction method and the highest retention time of AlS3PC in normal cells and tumor cells was obtained. In good times, another set of data on the test was used to establish a model of cell membrane permeability that accounts for the affinity of tumor cells for AlS3PC.