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目的探讨快速检测血清肠道EV71病毒抗体在临床诊断手足口病患儿中的价值。方法选取我院2013年2月~2014年2月间收治的手足口病患儿168例为研究对象,均采取胶体金免疫层析法对EV71特异性Ig M进行检测,观察检测结果。结果 2~3岁和3~4岁年龄段患儿EV71-Ig M检测阳性率较高,分别为52.8%和34.4%,其次为1~2岁年龄段患儿,阳性率为30.0%,5岁以上及小于1岁患儿的阳性率则较低,分别为20.0%和22.9%;男性患儿的EV71-Ig M检测阳性率为37.0%,女性患儿为33.8%,两组间阳性率比较差异无统计学意义,(P>0.05)。结论快速检测血清肠道EV71病毒抗体,操作简单、耗时短,对诊断手足口病有一定的临床应用价值。
Objective To investigate the value of rapid detection of serum EV71 virus in clinical diagnosis of hand-foot-mouth disease in children. Methods A total of 168 children with hand-foot-mouth disease admitted from February 2013 to February 2014 in our hospital were enrolled in this study. The EV71-specific IgM was detected by colloidal gold immunochromatography. The test results were observed. Results The positive rates of EV71-Ig M in children aged 2 to 3 and 3 to 4 years old were 52.8% and 34.4% respectively, followed by children aged 1-2 years with a positive rate of 30.0% and 5 The positive rates of children younger than 1 year old and younger than 1 year old were 20.0% and 22.9% respectively. The positive rate of EV71-Ig M was 37.0% in males and 33.8% in females, the positive rate The difference was not statistically significant (P> 0.05). Conclusion Rapid detection of serum EV71 virus antibody is simple, time-consuming and has certain clinical value in the diagnosis of HFMD.