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本文报告9例食管与胃的双原发癌。术前X线钡餐造影仅发现食管癌,术后病理检查,在贲门部又发现有另一个原发癌。其中食管病变均为鳞状细胞癌,且为晚期病变。贲门部病变中,8例为腺癌或腺鳞癌,1例为食管与贲门的双原发鳞状细胞癌。双原发癌间的距离为2～7厘米。在7例已经随访的病例中,2例术后10年健在。作者简要地复习了有关食管、胃双原发癌的文献,认为生癌野(Field Cancerization)学说值得重视;并提出在食管癌诊断与处理的过程中,必须注意相邻器官另一个原发癌存在的可能性。
This article reports 9 cases of double primary cancer of the esophagus and stomach. Preoperative X-ray barium meal imaging found only esophageal cancer. Postoperative pathological examination revealed another primary cancer in the cardia. Which esophageal lesions are squamous cell carcinoma, and late lesions. In the cardia lesions, 8 cases were adenocarcinoma or adenosquamous carcinoma, and 1 case was double primary squamous cell carcinoma of the esophagus and cardia. The distance between double primary cancers is 2-7 cm. Of the 7 cases that had been followed up, 2 were alive at 10 years postoperatively. The author briefly reviewed the literature on double primary cancers of the esophagus and stomach and considered that the theory of the field cancerization deserves attention; and proposed that during the diagnosis and treatment of esophageal cancer, another primary cancer of the adjacent organs must be observed. The possibility of existence.