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本文讨论了18例膀胱腺癌的临床及病理特点,其中原发性膀胱腺癌16伊1,转移性癌2例。男性患者14例,女性4例。发病年龄45~71岁,平均54岁。临床症状除排粘液尿而提示粘液腺癌外,其余症状无特异性。16伊1原发性膀胱腺癌中6例行单纯肿块切除术,另10创作膀胱部分切除术。膀胱腺癌总的5年生存率为33%。组织形态31.单纯型14例(管状腺癌8例,乳头状腺癌4例,粘液腺癌2例);2.混合型4例(均为腺癌和移行细胞癌混合)。随访结果发现混合型预后较好,而单纯型预后较差。粘液组织化学染色证明,膀胱腺癌多含唾液酸粘液,而少含中性粘液。研究结果还提示CEA免疫组化染色对估计膀胱腺癌的预后具有一定意义。
This article discusses the clinical and pathological features of 18 cases of adenocarcinoma of the bladder, including 16 cases of primary cystadenocarcinoma and 2 cases of metastatic carcinoma. 14 males and 4 females. The age of onset 45 to 71 years, mean 54 years. Clinical symptoms in addition to mucus and urine prompted mucinous adenocarcinoma, the remaining symptoms are nonspecific. 16 Iraq 1 primary cystadenocarcinoma in 6 cases of simple tumor resection, the other 10 cases of partial bladder resection. The overall 5-year survival rate of bladder adenocarcinoma was 33%. Organizational form 31. 14 cases of simple type (tubular adenocarcinoma in 8 cases, 4 cases of papillary adenocarcinoma, mucinous adenocarcinoma in 2 cases); Mixed 4 cases (both adenocarcinoma and transitional cell carcinoma mixed). Follow-up results found that the mixed prognosis is better, while the simple type of prognosis is poor. Mucin histochemical staining proved that bladder adenocarcinoma contains sialic acid mucus, and less with neutral mucus. The results also suggest that CEA immunohistochemical staining for the evaluation of the prognosis of bladder adenocarcinoma has some significance.