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C-反应蛋白(CRP)和血清淀粉样-A蛋白(SAA)是人体急性期反应最显著的蛋白质。可用放射免疫检测法进行测定。借此可发现损伤、肿瘤形成和感染性疾病。作者回顾性地收集一组病人的CRP,其中包括支气管扩张24例;肺气肿23例;支气管肺癌20例;包囊虫病(未破裂)7例;结核瘤和曲菌病各4例。结果显示:支气管扩张甚至缓解期的病人,其CRP水平明显高于肺气肿(包括缓解期和加重期在内)病人(P<0.02)。在支气管扩张的感染期,CRP中值超过65mg/L,比缓解期(30mg/L)高,但不显著。SAA测定值同样也是支气营扩张缓解期病人的中值220单位/L,显著高于肺气肿病人(P<0.01)。CRP与SAA之间呈正相关(r=0.92)。
C-reactive protein (CRP) and serum amyloid-A protein (SAA) are the most prominent proteins in the human acute phase. Available radioimmunoassay method for determination. It is possible to detect lesions, tumor formation and infectious diseases. The authors retrospectively collected a group of patients with CRP, including bronchiectasis in 24 cases; emphysema in 23 cases; bronchogenic carcinoma in 20 cases; cysticercosis (unruptured) in 7 cases; tuberculosis and aspergillosis in 4 cases. The results showed that patients with bronchiectasis or even remission had significantly higher CRP levels than patients with emphysema (including remission and exacerbations) (P <0.02). In bronchodilator infection, CRP median more than 65mg / L, than the remission (30mg / L) high, but not significant. The SAA was also significantly higher in patients with emphysema than in patients with emphysema (median, 220 units / L, P <0.01). There was a positive correlation between CRP and SAA (r = 0.92).