非风湿性房颤使卒中危险增加5倍,约达每年5%。作者运用病例一对照研究的方法,以识别非风湿性房颤病人患卒中的危险因素。据美马萨诸塞州综合医院1979年1月～87年12月的出院记录,选定非风湿性房颤和缺血性卒中134例作为病例组。这些患者均符合卒中的定义,该组除外(1)既往卒中史;(2)二尖瓣狭窄的体征或超声心动图表现,风湿性心脏病史;(3)既往栓塞现 Non-rheumatic atrial fibrillation increases the risk of stroke by a factor of 5, reaching about 5% per year. The authors used a case-control study to identify risk factors for stroke in patients with non-rheumatic atrial fibrillation. According to the Massachusetts General Hospital from January 1979 to December 1987 discharge records, selected 134 cases of non-rheumatic atrial fibrillation and ischemic stroke as a case group. All of these patients met the definition of stroke with the exception of (1) previous stroke history; (2) signs or echocardiographic manifestations of mitral stenosis, a history of rheumatic heart disease; (3) past embolism