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对动物和人体研究表明,感染弯曲菌后机体可产生特异性免疫力,且保护作用与血清型特异性免疫原有关。对数种通过粘膜免疫防御弯曲菌感染的方法进行了评估,目前认为口服灭活全细胞菌苗加佐剂[产肠毒素性大肠杆菌(ETEC)的不耐热毒素]最有希望。弯曲菌菌苗的研制与当前研制霍乱菌苗和ETEC菌苗的努力有关联。
Animal and human studies have shown that the body can produce specific immunity after Campylobacter infection, and the protective effect and serum-specific immunogens. Several methods of mucosal immunization against Campylobacter were evaluated, and oral inactivation of whole-cell vaccine plus adjuvant [heat-labile toxin of enterotoxigenic Escherichia coli (ETEC)] is now most promising. The development of Campylobacter strains is linked to the current efforts to develop cholera vaccine and ETEC vaccine.