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为评价长期应用多沙唑嗪治疗良性前列腺增生症(BPH)的有效性,Dutkiewicz S等进行了一项药物对照研究,长疗程应用多沙唑嗪(4mg／d)治疗64例非卧床BPH患者。使用多沙唑嗪72周且将持续使用。对照组23例,用盐酸哌唑嗪(4mg／d)治疗24周。多沙唑嗪(第一组)和哌唑嗪(第二组)结果相似,两组最大和平均尿流量分别增加了44．8％和43．5％,残尿量分别下降了72．0％和74．5％,梗阻症状减轻了89．6％和92盘％,以及刺激症状缓解了81．6％和
To evaluate the long-term efficacy of doxazosin in the treatment of benign prostatic hyperplasia (BPH), Dutkiewicz S et al. Conducted a controlled phase study of long-term treatment with doxazosin (4 mg / d) in 64 patients with ambulatory BPH . Doxazosin is used for 72 weeks and will continue to be used. Control group, 23 cases, with prazosin hydrochloride (4mg / d) for 24 weeks. The results for doxazosin (group 1) and prazosin (group 2) were similar, with the maximal and mean urinary flow increased by 44.8% and 43.5%, respectively, and the residual urine output decreased by 72.0 % And 74.5%, symptoms of obstruction reduced by 89.6% and 92%, and irritation alleviated by 81.6% and