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重复性好、梗塞体积稳定、成功率高的大鼠大脑中动脉梗塞再灌注模型是局灶性脑缺血研究的基础。目前使用的模型有穿线法、套线法等。夹闭法即使用微型动脉夹夹闭大鼠大脑中动脉（ＭＣＡ）是一种较好的方法，此方法可形成较稳定的梗塞灶，同时此模型对大鼠全身的影响较小，存活
Repeatability, infarction volume and high success rate of middle cerebral artery occlusion and reperfusion model in rats is the basis of focal cerebral ischemia study. The current model used threading method, line method and so on. Clipping method that the use of micro-artery clip in the middle cerebral artery occlusion of rats (MCA) is a better method, this method can form a more stable infarction, while the impact of this model on the whole body of the smaller rats, survival