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目的探讨多发性骨髓瘤(MM)诊断失误的原因,总结其临床特点及防治措施。方法回顾性分析误诊误治的12例MM病例。结果 12例患者最终皆诊断为MM,但均因不同临床表现而误诊为肾功能不全、骨质疏松及骨折、肿瘤占位性病变、高粘滞综合征和肺部感染。结论 MM为浆细胞病的一种,因单克隆免疫球蛋白分泌与否,分为分泌型MM和不分泌型MM,临床表现多种多样,千差万别,故需反复分析病情完善相关检查,防止误诊误治。
Objective To investigate the causes of misdiagnosis of multiple myeloma (MM) and to summarize its clinical features and prevention measures. Methods Retrospective analysis of misdiagnosis and mistreatment of 12 cases of MM. Results All 12 patients were diagnosed as MM eventually, but all were misdiagnosed as renal insufficiency, osteoporosis and fracture, tumor space occupying lesions, hyperviscosity syndrome and pulmonary infection due to different clinical manifestations. Conclusion MM as a plasma cell disease, due to the secretion of monoclonal immunoglobulin or not, is divided into secretory MM and non-secreting MM, a variety of clinical manifestations, vary widely, it is necessary to repeatedly analyze the condition to improve the relevant checks to prevent misdiagnosis Wrong treatment.