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用补阳还五汤治疗急性（发病２ｄ以内）脑梗死患者３５例，观察治疗前后血浆内皮素（ＥＴ）、降钙素基因相关肽（ＣＧＲＰ）水平，并与正常对照组进行对比。治疗前血浆ＥＴ、ＣＧＲＰ水平与正常人相比有显著差异（Ｐ＜０．０１），治疗后则显著改善（Ｐ＜０．０１），且在基本治愈组、有效组、无效组中亦有显著差异（Ｐ＜０．０５，Ｐ＜０．０１），改善程度基本治愈组＞有效组＞无效组。ＥＴ、ＣＧＲＰ值又可作为评估疗效的有价值指标。
Using Wuyang Huanwu Decoction in treating 35 patients with acute cerebral infarction (within 2 days), the levels of plasma endothelin (ET) and calcitonin gene-related peptide (CGRP) before and after treatment were observed and compared with the normal control group. Before treatment, plasma ET and CGRP levels were significantly different from normal subjects (P<0.01), and significantly improved after treatment (P<0.01), and also in the basic cure group, effective group, and invalid group. Significant difference (P <0.05, P <0.01), degree of improvement of the basic cure group> effective group> invalid group. ET and CGRP values can be used as valuable indicators for evaluating efficacy.