在动脉粥样硬化斑块形成和血脂紊乱的基础上,常伴随着血小板的异常激活。血小板参与了动脉粥样硬化斑块形成的全部过程,即血小板本身具有致斑块性,血小板参与体内血脂调节、促炎症及致氧化应激作用。该文介绍血小板致动脉粥样硬化斑块形成的机制和相关临床研究。 In the formation of atherosclerotic plaque and dyslipidemia, often accompanied by abnormal activation of platelets. Platelet involved in the formation of atherosclerotic plaque all the processes, that is plaque itself plaque, platelets involved in the regulation of blood lipids, pro-inflammatory and oxidative stress. This article describes the mechanism of platelet-induced atherosclerosis plaque formation and related clinical studies.