作者报告了1例伴有一过性脂蛋白代谢异常的先天梅毒病例。在1980～1995年间的文献中未见类似报告。 患者是一因肝脾肿大而就诊的3.5个月大的女婴。体检发现患儿皮肤苍白,肝肋下6cm,脾肋下5cm,此外未见其它临床异常。实验室检查显示:血沉128mm/h、贫血(红细胞1.2×10~(12)/L)、轻度血小板减少(血小板129×10~9/L)、白细胞计数正常;肝功能试验、血清白蛋 The authors report a case of congenital syphilis with transient lipoprotein metabolism. No similar reports were found in the literature from 1980 to 1995. The patient is a 3.5-month-old girl who has had an enlarged liver and spleen. Physical examination found that children with pale skin, liver ribs 6cm, 5cm spleen ribs, in addition, no other clinical abnormalities. Laboratory tests showed that ESR was 128 mm / h, anemia (erythrocyte 1.2 × 10-12 / L), mild thrombocytopenia (platelet 129 × 10-9 / L), normal white blood cell count, liver function test, serum albumin