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The purpose of this review is to examine the interaction of the limbic system and the cellular immune system from the perspective of evolutionary biology. While the limbic system exerts a level of control over the stress response systems, the cellular immune system spearheaded by the monocyte-macrophage is responsible for the acute phase response to threat.The potential role of the macrophage in certain neuropsychiatric and psychosomatic disorders,including dementia,delirium, schizophrenia, depression and autoimmune disease will be
The purpose of this review is to examine the interaction of the limbic system and the cellular immune system from the perspective of evolutionary biology. While the limbic system exerts a level of control over the stress response systems, the cellular immune system spearheaded by the monocyte- macrophage is responsible for the acute phase response to threat. potential role of the macrophage in certain neuropsychiatric and psychosomatic disorders, including dementia, delirium, schizophrenia, depression and autoimmune disease will be