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目的探讨脱氧葡萄糖-正电子发射断层显像(F-18-fluoro-2-deoxyglucose positron emission tomography,FDG-PET)在鼻咽癌放疗后鼻咽颅底病变中的诊断价值。方法通过9例行FDG—PET、CT和(或)MRI检查,以及内镜下鼻咽颅底病灶探查活检术的鼻咽癌放疗后患者,比较FDG—PET、CT和(或)MRI与病理活检结果。结果9例鼻咽癌放疗后患者中CT和(或)MRI提示枕骨斜坡复发7例,可疑复发2例;FDG-PET鼻咽颅底有浓聚灶9例;病理确诊复发3例,慢性炎症和(或)骨组织部分坏死6例。PDG-PET诊断准确率是33．3％(3／9),假阳性率为66．7％(6／9)。结论FDG—PET对鼻咽癌放疗后鼻咽颅底病变诊断有一定假阳性率,确诊需根据内镜下的病理诊断。
Objective To investigate the diagnostic value of F-18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) in nasopharyngeal skull base disease after radiotherapy of nasopharyngeal carcinoma. Methods Nine patients undergoing radiofrequency ablation of FDG-PET, CT and / or MRI, as well as endoscopic nasopharyngeal skull base tumor biopsy, were compared with those of FDG-PET, CT and / or MRI Biopsy results. Results CT and / or MRI of 9 patients with nasopharyngeal carcinoma showed recurrent occipital slope in 7 cases and suspicious recurrence in 2 cases. There were 9 cases of focal necrosis in the skull base of FDG-PET nasopharyngeal carcinoma, 3 cases of pathological diagnosis and 3 cases of chronic inflammation And (or) bone tissue necrosis in 6 cases. The diagnostic accuracy of PDG-PET was 33.3% (3/9) and the false positive rate was 66.7% (6/9). Conclusion FDG-PET has a false positive rate in the diagnosis of nasopharyngeal skull base disease after radiotherapy for nasopharyngeal carcinoma. The diagnosis should be based on the pathological diagnosis of endoscopic diagnosis.