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目的研究宫颈癌病理组织中叶酸受体(FR-α)与Ki-67核蛋白的表达水平及相关性分析。方法选取2014年2月至2015年1月50例宫颈癌患者作为研究对象,50例均进行免疫组织学检查,比较FR-α与Ki-67核蛋白的表达水平及相关性。结果 50例宫颈癌患者中宫颈癌不同时期的FR-α的表达比较和Ki-67核蛋白的表达比较差异均未见统计学意义(P>0.05);FR-α和Ki-67核蛋白的表达比较差异有统计学意义(P<0.05)。结论宫颈癌病理组织中FR-α水平逐渐升高,且与Ki-67核蛋白的表达呈相关性。
Objective To study the expression levels of folic acid receptor (FR-α) and Ki-67 nucleoprotein in cervical cancer and its correlation analysis. Methods Fifty patients with cervical cancer from February 2014 to January 2015 were selected as the study subjects. Fifty patients underwent immunohistological examinations to compare the expression of FR-α and Ki-67 nucleoprotein and their correlation. Results The expression of FR-α in different stages of cervical cancer and the expression of Ki-67 showed no significant difference (P> 0.05) in 50 patients with cervical cancer. The expressions of FR-α and Ki-67 nucleoprotein The difference was statistically significant (P <0.05). Conclusions The level of FR-αin pathological tissues of cervical cancer is gradually increased, and it is correlated with the expression of Ki-67 nucleoprotein.