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目的:探讨孕期不同程度糖耐量异常与母儿并发症的关系。方法:1272例孕妇于孕24～28周行口服50g 葡萄糖筛查,血糖≥7.8mmol/L 者(159例)行口服75g 葡萄糖耐量试验。结果:妊娠期糖尿病(GDM)12例(0.94%),孕期糖耐量降低(GIGT)80例(6.29%)。GIGT 组妊娠高血压综合征(PIH)、巨大儿、剖宫术、产后病率及胎儿宫内窘迫的发生率低于 GDM 组,高于正常组,但差异无显著性(P>0.05).GIGT 诊断标准为:糖耐量试验中任何一项高于正常值以及2小时血糖值在6.6～9.1mmol/L 范围。糖筛查血糖值≥7.8mmol/L 组中,PIH、巨大儿及剖宫术的发生率均高于血糖值<7.8mmol/L 组,差异有显著性(P<0.05)。GDM 及 GIGT 的发生率随糖筛查血糖值的升高而升高。结论:孕期不同程度糖耐量异常与母儿并发症有一定的关系,应引起重视.
Objective: To investigate the relationship between different degrees of impaired glucose tolerance during pregnancy and maternal and child complications. Methods: A total of 1272 pregnant women underwent oral glucose 50 g glucose screening at 24-28 weeks of gestation, and 75 g oral glucose tolerance test (159 cases) with blood glucose ≥ 7.8 mmol / L. RESULTS: Twelve patients (0.94%) had gestational diabetes mellitus (GDM) and 80 patients (6.29%) had impaired glucose tolerance during pregnancy (GIGT). The incidence of pregnancy induced hypertension (PIH), macrosomia, cesarean section, postpartum morbidity and fetal distress in GIGT group was lower than that in GDM group, but not significantly higher than that in normal group (P> 0.05). GIGT diagnostic criteria: glucose tolerance test any one above normal and 2-hour blood glucose in the 6.6 ~ 9.1mmol / L range. The incidence of PIH, macrosomia and cesarean section were higher than those of blood glucose <7.8mmol / L group (P <0.05). The incidence of GDM and GIGT with sugar screening increased blood glucose values. Conclusion: Different degrees of gestational impaired glucose tolerance and maternal and child complications have a certain relationship, should pay attention.