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端粒酶是一种核糖核蛋白酶。在大部分正常人体细胞中无端粒酶活性,而在人类多种肿瘤中发现有表达。p53基因对诱导细胞凋亡起关键作用,并被认为可能与端粒酶活性有关。日本Tottori大学医院为评价端粒酶活性与上皮性卵巢癌进展和扩散是否相关以及p53基因和端粒酶活性的关系进行了研究。 1993～1996年在该院行卵巢切除术的53例为
Telomerase is a ribonucleoprotein enzyme. In most normal human cells without telomerase activity, but found in a variety of human tumors. The p53 gene plays a key role in inducing apoptosis and is thought to be associated with telomerase activity. Tottori University Hospital in Japan to evaluate the telomerase activity and epithelial ovarian cancer progression and proliferation is related to p53 and telomerase activity was studied. 53 cases of ovariectomy in the hospital from 1993 to 1996