二尖瓣返流的严重程度部份取决于左室射血所面对的主动脉阻抗。硝普钠具有扩张动脉和静脉的双重作用,既降低周围血管阻力,亦增加静脉容量,因此其减低二尖瓣返流量的确切作用难以肯定。本文用能降低周围血管阻力而对静脉血管床作用很小的肼苯哒嗪,研究其对严重二尖瓣返流的血液动力学效应,并探讨口服肼苯哒嗪能否作为二尖瓣返流的一种治疗方法。方法:10例严重二尖瓣返流病例,其中5例在休息时即有呼吸困难,5例在轻度行动时出现气短。心室容积按左室双面造影的舒张末期和收缩末期心 The severity of mitral regurgitation depends in part on the impedance of the aorta facing left ventricular ejection. Sodium nitroprusside has the dual effects of dilating arteries and veins, reducing peripheral vascular resistance and increasing venous volume, so it is difficult to confirm the exact role of sodium nitroprusside in reducing the amount of mitral regurgitation. In this paper, can reduce the peripheral vascular resistance and venous vascular bed role of small hydralazine study its severe hemodynamic effects of mitral regurgitation and to investigate whether oral hydralazine can be used as mitral valve return Flow of a treatment. Methods: Ten patients with severe mitral regurgitation were involved. Five of them had dyspnea at rest and five had shortness of breath during mild exercise. Ventricular volume by left ventricular double-sided angiography end-diastolic and end systolic heart