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硝酸戊四醇酯(1、3—戊二酸—2,2—双[(硝基氧基)甲基]二硝酸酯)为心绞痛病人预防用的心冠状血管扩张剂。硝酸戊四醇酯测定方法计有容量法、分光光度法、滴定分析法、极谱法、电位分析法及色谱法。片剂中硝酸戊四醇酯的药典测定法为分光光度法。本文报导了一种灵敏的用分光光度法测定片剂中硝酸戊四醇酯的方法。锌及二氯化钙与硝酸戍四醇酯还原,生成的亚硝基化合物在酸性情况下与萘胺作用,所得紫色产物在545nm
Pentaerythritol nitrate (1,3-glutaric acid 2,2-bis [(nitrooxy) methyl] dinitrate) is a cardioprotective agent for the prevention of angina pectoris. Nitric acid pentaerythritol determination of the total volume method, spectrophotometry, titration, polarography, potential analysis and chromatography. Pharmacopoeial determination of pentaerythritol nitrate in tablets is spectrophotometry. This paper reports a sensitive method for spectrophotometric determination of pentaerythrityl nitrate in tablets. Zinc and calcium dichloride and garnet nitrate nitrate reduction, the resulting nitroso compounds in the case of naphthylamine and acidic effect, the resulting purple product at 545nm