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观察氟芬合剂合并硝酸甘油滴鼻减轻气管内插管的心血管反应情况。４５例病人分为三组，每组１５例。Ⅰ组单纯应用东莨菪硷、安定、氟芬合剂及琥珀胆碱进行全麻诱导，气管内插管。Ⅱ组和Ⅲ组全麻诱导用药同Ⅰ组，只是在注射琥珀胆硷之前，分别经鼻滴入硝酸甘油０．６ｍｇ和０．８ｍｇ。用ＣａｒｄｉｏｃａｐⅡ型多功能监护仪，记录全麻诱导前后ＨＲ、ＳＢＰ、ＤＢＰ、ＭＡＰ和ＲＰＰ等指标。结果表明，氟芬合剂加用硝酸甘油滴鼻能更好地降低诱导插管时的心血管反应，且硝酸甘油用量０．８ｍｇ组优于０．６ｍｇ组。从而认为此法对于合并冠心、高血压病人气管内插管时心血管反应无疑具有较好的预防作用。
To observe the combination of flutamide and nitroglycerin to reduce the cardiovascular response of endotracheal intubation. 45 patients were divided into three groups, 15 cases in each group. Group Ⅰ simple application of scopolamine, diazepam, fenfen mixture and succinylcholine for general anesthesia induction, endotracheal intubation. Group Ⅱ and group Ⅲ induction of general anesthesia with the same group Ⅰ, except that before the injection of succinylcholine, nitroglycerin 0.6mg and nasal drops of 0.8mg. Cardiocap Ⅱ multi-function monitor was used to record HR, SBP, DBP, MAP and RPP before and after induction of general anesthesia. The results showed that flurbine mixture plus nitroglycerin nasal drops can be better to reduce the cardiovascular response induced intubation, and the amount of nitroglycerin 0.8mg group was better than the 0.6mg group. So that this method for the merger of coronary heart disease, hypertensive patients with endocardial cardiopulmonary reaction will undoubtedly have a better preventive effect.