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目的:探讨利培酮和奥氮平治疗少年儿童首发精神分裂症的疗效情况。方法:采用回顾性分析的方法,分析我院收治的少年儿童首发精神分裂症患者临床资料,依据治疗方式不同分为利培酮组和奥氮平组。结果:利培酮组和奥氮平组治疗后阳性症状、阴性症状、精神病理及总分无明显差异,利培酮组和奥氮平组治疗后语言智商、操作情商、总智商分均无显著性差异(P>0.05)。结论:利培酮和奥氮平治疗少年儿童首发精神分裂症的疗效均较为明显,值得临床推广应用。
Objective: To investigate the efficacy of risperidone and olanzapine in the treatment of first-episode schizophrenia in children. Methods: The clinical data of schizophrenics in children and adolescents admitted to our hospital were analyzed retrospectively. According to the different treatment methods, they were divided into risperidone group and olanzapine group. Results: There were no significant differences in positive symptoms, negative symptoms, psychopathology and total score between risperidone group and olanzapine group after treatment, and there was no significant difference between risperidone group and olanzapine group after treatment Significant difference (P> 0.05). Conclusion: The efficacy of risperidone and olanzapine in the treatment of first-episode schizophrenia in children and adolescents are both obvious and worthy of clinical application.