目的 :探讨重症急性胰腺炎 (SAP)采用中西医结合方法治疗的临床意义。方法 :我院外科 1995年6月至 2 0 0 3年 6月间收治SAP 136例 ,随机分成研究组和对照组各 6 8例 ,对照组早期采用传统的方法治疗 ,研究组在传统治疗方法的基础上应用通腑攻下方点滴法保留灌肠 ,对比分析两组的并发症发生率、中转手术率和病死率。结果 :①研究组并发症发生率 ( 4 2 .6 % )比对照组 ( 6 0 .3% )明显降低 (P <0 .0 5 )。②研究组早期胰外脏器损害的发生率 ( 2 6 .5 % ) ,也比对照组 ( 4 8.5 % )显著降低 (P <0 .0 1)。③中转手术率研究组 ( 13.2 % )比对照组 ( 2 3.5 % )相对降低 ,但无显著差异 (P >0 .0 5 )。④病死率研究组 ( 11.6 % )亦较对照组 ( 2 5 .0 % )显著降低 (P <0 .0 5 )。结论 :SAP早期应用中西医结合方法治疗有明显作用 ,其病死率为 11.6 % ,比对照组明显降低 ,可作为SAP的综合治疗的重要部分 ,有良好的应用前景 Objective: To investigate the clinical significance of treatment of severe acute pancreatitis (SAP) by integrated traditional Chinese and western medicine. Methods: One hundred and sixty-six patients with SAP were enrolled in our hospital from June 1995 to June 2003, and were randomly divided into study group and control group with 68 cases in each group. The control group was treated with traditional method at an early stage. In the traditional treatment group Based on the application of Tongfu off the drip method to retain the enema, comparative analysis of the two groups of complications, the rate of surgery and mortality in the transfer. Results: ① The incidence of complications in study group (42.6%) was significantly lower than that in control group (60.3%) (P <0.05). ② The incidence of early pancreatic organ damage in the study group (26.5%) was also significantly lower than that in the control group (8.5%) (P <0.01). (3) The rate of transit surgery in the study group (13.2%) was lower than that in the control group (23.5%), but there was no significant difference (P> 0.05). ④The mortality of the study group (11.6%) was also significantly lower than that of the control group (25.0%) (P <0.05). Conclusion: The early application of integrated traditional Chinese and western medicine has a significant effect on the treatment of SAP, the mortality rate was 11.6%, significantly lower than the control group, SAP can be used as an important part of the comprehensive treatment, has a good prospect