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我们从1997年7月至1999年2月采用吡柔比星(THP)为主方案治疗晚期胃癌26例,对其疗效和毒副作用进行了观察,现报告如下。 1 材料与方法 1.1 病例:全组26例均经胃肠钡餐(GI),纤维胃镜,手术切除或剖腹探查等病理确诊。26例中,男性17例,女性9例,年龄38～72岁,平均53岁。其中手术剖腹16例,切除胃癌病灶12例,4例未能切除。B超示腹主动脉旁淋巴结转移12例,肝转移8例,中至大量腹水5例,肺转移5例,合并胸水2例,左锁骨上淋巴结转移6例。全组患者Karnofsky评分为60～90分。 1.2 治疗方法:根据病人身体状况,给予
From July 1997 to February 1999, 26 patients with advanced gastric cancer were treated with pirarubicin (THP) as the main regimen. The efficacy and side effects were observed. The report is as follows. 1 Materials and Methods 1.1 Cases: All the 26 cases were diagnosed by gastrointestinal barium meal (GI), gastroscopy, surgical resection or laparotomy. In 26 cases, there were 17 males and 9 females, aged 38-72 years, with an average age of 53 years. Incision laparotomy in 16 cases, removal of gastric cancer lesions in 12 cases, 4 cases failed to remove. B-mode ultrasound showed 12 cases of para-aortic lymph node metastases, 8 cases of liver metastases, 5 cases of moderate to large ascites, 5 cases of lung metastases, 2 cases of pleural effusion, and 6 cases of left supraclavicular lymph node metastasis. The Karnofsky score for the entire group was 60-90 minutes. 1.2 Treatment: According to the patient’s physical condition, given