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目的探讨“寿星宝”保健酒对老龄小鼠的抗氧化作用。方法 80只昆明种老龄小鼠随机分成4组:即老龄对照组、保健酒低剂量组、保健酒中剂量组、保健酒高剂量组,各组分别连续灌胃90d后,分别测定小鼠血清中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活力和丙二醛(MDA)含量。结果与老龄对照组相比,保健酒低、中、高剂量组均能明显提高小鼠血清SOD活力、GSH-Px活力及降低MDA含量。其中高、中剂量组功效较低剂量组显著,而高剂量组和中剂量组功效相当。结论 “寿星宝”保健酒对老龄小鼠具有抗氧化的作用,可延缓小鼠衰老。
Objective To investigate the anti-oxidative effect of “Shuxingbao” health wine on aged mice. Methods Eighty Kunming elder mice were randomly divided into 4 groups: the aged control group, the health-care wine low-dose group, the health-care wine middle-dose group and the health wine high-dose group. (SOD), glutathione peroxidase (GSH-Px) activity and malondialdehyde (MDA) content were measured. Results Compared with the aged control group, low, medium and high dose health wine group could significantly increase SOD activity, GSH-Px activity and MDA content in mice serum. Among them, the high-dose group and middle-dose group had lower efficacy, while the high-dose group and middle-dose group had the same effect. Conclusion “Shou Xing Bao ” health wine on the aging mice with anti-oxidation, can delay the aging mice.