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为了揭示脂质代谢在动脉血栓性脑梗塞和脑出血之间的并同;及其与不同部位梗塞的关系,评价脂质在脑血管病中的作用。采用酶法对544例不同民族的急性脑血管病(梗塞463例,出血81例)做了血脂分析,并与对照组407例进行比较。结果显示:脑梗塞组和脑出血组的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL—C)及总胆固醇与高密度脂蛋白胆固醇的比值(TC/HDL—C)均非常显著高于对照组(P<0.001),脑梗塞组的HDL—C非常显著低于对照组(P<0.001);梗塞组和出血组之间、及梗塞组中深穿支闭塞亚组与皮层支闭塞亚组之间各血脂成分对比,无显著差异(P>0.05);单纯脑血管病组及合并高血压、糖尿病、冠心病组分别与正常组对比、单纯脑血管病组与脑血管病各合并症组对比,差异不一,提示血脂异常是脑血管病不可忽视的因素。脂质与脑血管病的关系,复杂而有待于深入研究。
In order to reveal the correlation between lipid metabolism in arterial thrombotic cerebral infarction and intracerebral hemorrhage and its relationship with infarction in different sites, the role of lipids in cerebrovascular disease was evaluated. 544 patients with acute cerebrovascular disease of different nationalities (463 cases of infarction and 81 cases of hemorrhage) were analyzed by enzymatic method, and compared with 407 cases of control group. The results showed that the ratio of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and total cholesterol to high density lipoprotein cholesterol (TC / HDL- C) were significantly higher than those in the control group (P <0.001). HDL-C in cerebral infarction group was significantly lower than that in the control group (P <0.001). The occlusion group and the bleeding group, There was no significant difference between the subgroups and the cortical branch occlusion subgroups (P> 0.05). Compared with the normal group, the patients with simple cerebrovascular disease and with hypertension, diabetes mellitus and coronary heart disease group were simple cerebrovascular disease group And cerebrovascular disease complication group contrast, different, suggesting that dyslipidemia is a non-neglected factors of cerebrovascular disease. The relationship between lipid and cerebrovascular disease is complicated and needs further study.