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目的探讨2型糖尿病(T2DM)患者微量白蛋白尿与冠心病(CHD)的关系。方法70例T2DM患者,依有无并发CHD分为糖尿病并CHD组(22例)和糖尿病不并CHD组(48例),分析比较两组心血管疾病危险因素。再依微量白蛋白尿含量分为微量白蛋白尿组(28例)和非白蛋白尿组(42例),比较两组CHD的发生率。结果糖尿病并CHD微量白蛋白尿含量明显高于不并CHD组〔(96.71±45.87)mg/L∶(9.77±5.94)mg/L,P<0.01〕;微量白蛋白尿组并发CHD的发生率显著高于非白蛋白尿组(46.43%∶21.43%,P<0.05)。结论检测微量白蛋白尿是预测T2DM患者CHD发病率的有意义的指标。
Objective To investigate the relationship between microalbuminuria and coronary heart disease (CHD) in type 2 diabetes mellitus (T2DM). Methods Seventy patients with T2DM were divided into diabetes mellitus (CHD) group (n = 22) and diabetes mellitus without CHD group (n = 48) according to the presence of CHD. The risk factors of cardiovascular disease were analyzed. The patients were divided into microalbuminuria group (n = 28) and non-albuminuria group (n = 42) according to the microalbuminuria content. The incidence of CHD was compared between the two groups. Results The diastolic blood pressure and CHD microalbuminuria were significantly higher than those in the non-CHD group (96.71 ± 45.87 mg / L, 9.77 ± 5.94 mg / L, P <0.01). The incidence of CHD in patients with microalbuminuria Significantly higher than the non-albuminuria group (46.43%: 21.43%, P <0.05). Conclusion The detection of microalbuminuria is a significant indicator of the incidence of CHD in patients with T2DM.