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目的：探讨院外、院内一体化救治模式对急性冠脉综合征(ACS)患者救治效果。方法应用一体化救治模式703例ACS患者为研究组,非一体化救治模式508例ACS为对照组。结果研究组临床好转率为73.12%，死亡率为12.52%，溶栓627例(89.19%)、1 h内溶栓173例(27.59%)、1~3 h内溶栓297例(47.37%)、3~6h溶栓148例(23.6%)，6 h以上溶栓9例(1.44%)、溶栓再通467例(74.48%，对照组临床好转率为62.6%。死亡率为19.49%，溶栓332例(65.35%)、1 h内溶栓28例(8.43%)、1~3 h内溶栓91例(27.41%)、3~6 h溶栓130例(39.16%)，6 h以上的溶栓83例(25%)、溶栓再通206例(62.05%)，两组参数间差异有统计学意义。结论一体化救治组的ACS患者治疗率较传统救治组提高、入院溶栓准备时间缩短，患者的临床好转率增高、死亡率下降。“,”Objective To investigate the effectiveness of the integrative treatment model for acute coronary syndrome (ACS) in pre-hospital and in-hospital phases. Methods The study group of 703 ACS patients was treated with integrative collaborative treatment model while the control group of 508 ACS patients was treated with conventional treatment model. Results For the study group, it reflected an improvement rate of 73.12%, a mortality of 12.52%; in 627 cases of the group which received thrombolytic therapy, it resulted in 1-hour thrombolysis rate of 27.59%(173/627), 1-3 hours thrombolysis rate of 47.37%(297/627), 3-6 hours thrombolysis rate of 23.6% (148/627), more than 6 hours thrombolysis rate of 1.44% (9/627), and the total recanalization of 74.48%(467/627). For the control group, it reflected an improvement rate of 62.6%, a mortality rate of 19.49%;in 332 cases of the group which received thrombolytic therapy, it reflected 1-hour thrombolysis rate of 8.43%(28/332), 1-3 hours thrombolysis rate of 27.41% (91/332), 3-6 hours thrombolysis rate of 39.16% (130/332), more than 6 hours thrombolysis rate of 25% (83/332), and the total recanalization of 62.05% (206/332). Conclusion The integrative treatment model may increase the total improvement rate and decrease the mortality of the patients with ACS, and simultaneously, it may also shorten the time for thrombolysis.