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目的探讨氨基末端B型利钠肽前体(NT-proBNP)对急性呼吸困难的诊断价值。方法将464例急性呼吸困难患者,根据临床资料及心脏超声心动图分为急性充血性心力衰竭组(急性心衰组)及非心衰组,测定并比较两组患者NT-proBNP的水平,评价其对急性呼吸困难鉴别诊断的价值。结果急性心衰组243例,非心衰组221例,NT-proBNP分别为(2484.4±102.5)pg/ml和(248.6±9.5)pg/ml,两组比较具有显著性差异(P<0.001)。以NT-proBNP≥3849pg/ml为阳性,诊断急性充血性心力衰竭的灵敏度为92.6%,特异度为86.3%。结论急诊常规检测NT-proBNP有利于对急性呼吸困难患者做出快速诊断,有助于鉴别急性呼吸困难是否为急性充血性心力衰竭所致。
Objective To investigate the diagnostic value of NT-proBNP for acute dyspnea. Methods 464 patients with acute dyspnea were divided into acute congestive heart failure group (AHF group) and non-heart failure group according to clinical data and echocardiography. The levels of NT-proBNP in both groups were measured and compared. Its differential diagnosis of acute dyspnea value. Results There were 243 cases in acute heart failure group and 221 cases in non-heart failure group. NT-proBNP was (2484.4 ± 102.5) pg / ml and (248.6 ± 9.5) pg / ml, . NT-proBNP ≥ 3849pg / ml as a positive diagnosis of acute congestive heart failure was 92.6% sensitivity and specificity of 86.3%. Conclusion The routine examination of NT-proBNP in emergency is helpful for the rapid diagnosis of patients with acute dyspnea and is helpful to distinguish whether acute dyspnea is caused by acute congestive heart failure.