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目的观察肝癌动脉灌注与栓塞配合热疗的治疗效果。方法2002至2005年,对43例肝癌患者进行动脉超选灌注顺铂80mg、阿霉素20mg,然后经导管注入混有阿霉素40mg、丝裂霉素10mg的超液态碘油乳化剂进行栓塞,术后2小时、第4天、8天、12天、16天,运用WF-2102A微波热疗治疗仪进行配合治疗。每次40分钟,电脑显示测温要求在41℃～42℃之间。结果半年生存率(39/43)90%,一年生存率(27/43)62.7%,二年生存率(9/43)20.9%,三年生存率(6/43)13.9%,中位生存期16个月。结论肝癌动脉灌注与栓塞配合热疗临床观察表明,该方法疗效显著,应成为一项重要的非手术治疗方案。
Objective To observe the therapeutic effect of arterial perfusion and embolization combined with hyperthermia on liver cancer. Methods From 2002 to 2005, 43 cases of liver cancer patients underwent superselective perfusion of cisplatin 80mg and doxorubicin 20mg, and then transcatheter injection of doxorubicin 40mg, mitomycin 10mg ultra-liquid lipiodol emulsifier for embolization , 2 hours after surgery, 4 days, 8 days, 12 days, 16 days, using WF-2102A microwave hyperthermia treatment instrument for treatment. Every 40 minutes, the computer shows the temperature requirements between 41 ℃ ~ 42 ℃. Results The six-year survival rate (39/43) was 90%, the one-year survival rate was 27.7%, the two-year survival rate was 9.9%, and the three-year survival rate was 13.9% Survival of 16 months. Conclusion The clinical observation of arterial perfusion and embolization combined with hyperthermia in hepatocellular carcinoma shows that this method has significant curative effect and should become an important non-surgical treatment plan.