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目前,应用人免疫球蛋白制剂治疗各种疾病,在实践中得到较高的评价。然而目前商品的γ—球蛋白制剂,主要含有IgG和少量的其他种免疫球蛋白,而抗各种细菌病原体(志贺氏菌、沙门氏菌属、大肠杆菌)的抗体滴度却不很高,因为抗细菌抗体属于IgM,而制剂中含量不多。通常γ—球蛋白制剂对新生儿和婴儿的各种感染效果很差,新生儿及婴儿的特点是血中IgA和IgM的含量低下。复合免疫球蛋白制剂(CIP)含有50%～70%的IgG,15%～25%的IgM和IgA,具有高浓度的抗肠道杆菌(志贺氏菌、沙门氏菌属、大肠杆菌)的抗
At present, the application of human immunoglobulin preparations for the treatment of various diseases, in practice, get a higher rating. However, the γ-globulin preparations of the present products mainly contain IgG and a small amount of other immunoglobulins while the antibody titers against various bacterial pathogens (Shigella, Salmonella, and Escherichia coli) are not very high because Antibacterial antibodies belong to IgM, while the content of the preparation is small. Often, gamma-globulin preparations are ineffective at various infections in newborns and infants, and neonates and infants are characterized by low levels of IgA and IgM in the blood. Complex immunoglobulin preparations (CIPs) contain 50% to 70% of IgG, 15% to 25% of IgM and IgA and have high concentrations of anti-Enterobacter (Shigella, Salmonella, Escherichia coli)