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作者在19只家兔足背部及其周围皮肤涂抹湿润烧伤膏(MEBO),用行为测痛方法测定涂抹MEBO前后的痛阈的变化。结果发现,在涂抹MEBO后一定时间内,痛阈明显升高,经统计学处理P<0.001或0.01,而涂抹凡士林后,痛阈无明显变化P>0.05。由此说明MEBO参与了皮肤的镇痛作用。
The authors applied MEBO to the back of the foot and the surrounding skin of 19 rabbits, and determined the change of pain threshold before and after applying MEBO by means of behavioral pain test. The results showed that within a certain period of time after application of MEBO, the pain threshold was significantly increased, P <0.001 or 0.01 after statistical treatment, but there was no significant change in pain threshold after Vaseline administration (P> 0.05). This shows that MEBO is involved in the analgesic effect of the skin.